DRNAse® from Oncosimis Biotech Private Limited is an Endonuclease encoded by the same gene as Benzonase® from Merck-Millipore. But unlike Benzonase® which is a dimer, DRNAse® is a monomeric and thus unique in its nature of activity. DRNAse® cleaves all forms of DNA/RNA into smaller nucleotides in wider conditions of temperature, pH, buffers and detergents. Some forms of cell death, such as NETosis are characterized by the release of decondensed chromatin and granular contents to the extracellular space.

DRNAse® reduces the viscosity of wound surface, facilitating angiogenesis and healing. It has been demonstrated that diabetic mice have shown accelerated diabetic foot ulcer healing upon administration of endonuclease. Key benefits of DRNAse® include enhancing the synergistic activity of IGF-1, EGF & PGF and thus can be used as Anti-aging, anti-wrinkle, wound healing, anti-hair loss, hair growth applications.

Application: Vaccine manufacturing & Gene therapy
Purity: ≥ 98%