DRNAse
DRNAse® from Oncosimis Biotech Private Limited is an Endonuclease encoded by the same gene as Benzonase® from Merck-Millipore. But unlike Benzonase® which is a dimer, DRNAse® is a monomeric and thus unique in its nature of activity. DRNAse® cleaves all forms of DNA/RNA into smaller nucleotides in wider conditions of temperature, pH, buffers and detergents. Some forms of cell death, such as NETosis are characterized by the release of decondensed chromatin and granular contents to the extracellular space.
DRNAse® reduces the viscosity of wound surface, facilitating angiogenesis and healing. It has been demonstrated that diabetic mice have shown accelerated diabetic foot ulcer healing upon administration of endonuclease. Key benefits of DRNAse® include enhancing the synergistic activity of IGF-1, EGF & PGF and thus can be used as Anti-aging, anti-wrinkle, wound healing, anti-hair loss, hair growth applications.
Application: Vaccine manufacturing & Gene therapy
Purity: ≥ 98%
DNAse l
DNase I (Deoxyribonuclease I) is an endonuclease that catalyzes the hydrolysis of DNA, producing oligonucleotides. It is used to reduce viscosity in DNA-rich samples and to remove DNA from protein preparations or cell lysates.
Application: Cell-free DNA removal, gene therapy production, protein purification
T7 RNA Polymerase
T7 RNA Polymerase is a DNA-dependent RNA polymerase that specifically transcribes DNA downstream of a T7 promoter. It is widely used for in vitro RNA synthesis, including mRNA therapeutics and riboprobe generation.
Application: mRNA synthesis, in vitro transcription, synthetic biology
RNAse inhibitor
RNase Inhibitor binds to and inactivates RNase A-type enzymes, preventing RNA degradation in enzymatic reactions. It is essential in high-fidelity RNA work including RT-PCR, RNA-seq, and mRNA vaccine development.
Application: RNA protection in molecular biology workflows, RT-PCR & qRT-PCR assays, single-cell RNA analysis, RNA probe & synthetic RNA production
RNAse inhibitor
IPPase hydrolyzes inorganic pyrophosphate to orthophosphate, driving biosynthetic reactions forward by removing pyrophosphate byproducts. It is commonly used in PCR and nucleotide synthesis reactions.
Application: Nucleic acid synthesis, PPi hydrolysis, ligation reactions, DNA amplification, and enzymatic assays
| Sub Product | Details | Size | Price | |
| DRNAse | View Details | -- | ||
| DNAse l | View Details | -- | ||
| T7 RNA Polymerase | View Details | -- | ||
| RNAse inhibitor | View Details | -- | ||
| Inorganic Pyro Phosphatase | View Details | -- | ||